Friday, 15 April 2016

EFFECT OF IRON AND VITAMIN C FORTIFIED CANDIES ON THE IRON STATUS OF EARLY TEENAGER

Abstract: Iron deficiency anemia is the most nutrition problem in teenager period. One possible strategy to prevent iron deficiency anemia in this group is the fortification of favorite food as candy. So, this study was designed to know the effect of iron and vitamin C fortified candies on the iron status of teenager aged 10-16 y. The female teenager were randomly assigned to 3 treatment groups: A fortified group with iron (n = 20), fortified group with vitamin C (n = 20 ) and a control group (n = 20). Candy was given to the teenager every day for 12 wk, 5g (1 piece). The candy given to the fortified group contained 1 mg elemental Fe ( Ferric hydroxide) /g candy and 1 mg vitamin C (Ascorbic acid) / g candy . The results showed that the hemoglobin concentration of the fortified groups increased to 10.6 g/L and 11.2g/L in group 3 and from 10.6 to 12.8 in group 2 whereas that of the control group was 10.6 g/L. Anemia decreased from 50.9 % at the control group to 8.8% in group 2 and 13.3 in group 3 after 12 wk (P ≤0.05) and, the serum ferritin concentration was lower in the control group than the fortified groups with iron and vitamin C (P ≤0.05). From these results, it could be recommended that Iron and vitamin C fortified candies were effective for improving the iron status of teenager aged 10-16y and might be a good way to decrease iron deficiency in teenager of low-to-middle income groups. - See more at: http://www.journalijar.com/article/7371/effect-of-iron-and-vitamin-c-fortified-candies-on-the-iron-status-of-early-teenager./#sthash.FRpZ4RJ9.dpuf
Abstract: Iron deficiency anemia is the most nutrition problem in teenager period. One possible strategy to prevent iron deficiency anemia in this group is the fortification of favorite food as candy. So, this study was designed to know the effect of iron and vitamin C fortified candies on the iron status of teenager aged 10-16 y. The female teenager were randomly assigned to 3 treatment groups: A fortified group with iron (n = 20), fortified group with vitamin C (n = 20 ) and a control group (n = 20). Candy was given to the teenager every day for 12 wk, 5g (1 piece). The candy given to the fortified group contained 1 mg elemental Fe ( Ferric hydroxide) /g candy and 1 mg vitamin C (Ascorbic acid) / g candy . The results showed that the hemoglobin concentration of the fortified groups increased to 10.6 g/L and 11.2g/L in group 3 and from 10.6 to 12.8 in group 2 whereas that of the control group was 10.6 g/L. Anemia decreased from 50.9 % at the control group to 8.8% in group 2 and 13.3 in group 3 after 12 wk (P ≤0.05) and, the serum ferritin concentration was lower in the control group than the fortified groups with iron and vitamin C (P ≤0.05). From these results, it could be recommended that Iron and vitamin C fortified candies were effective for improving the iron status of teenager aged 10-16y and might be a good way to decrease iron deficiency in teenager of low-to-middle income groups. - See more at: http://www.journalijar.com/article/7371/effect-of-iron-and-vitamin-c-fortified-candies-on-the-iron-status-of-early-teenager./#sthash.FRpZ4RJ9.dpuf

Wednesday, 13 April 2016

ASSOCIATION BETWEEN VITAMIN D RECEPTOR GENE POLYMORPHISMS AND OSTEOPOROSIS IN POST MENOPAUSAL WOMEN ATTENDING ZAGAZIG UNIVERSITY HOSPITALS

Abstract: Aim:-To assess the association between the vitamin D receptor gene polymorphisms and osteoporosis in Egyptian postmenopausal women, to determine the genotypes most frequently associated with decreased bone mineral density and vertebral fracture. In addition, to assess the modulatory role of high daily calcium intake on the genetic predisposition of osteoporosis. Patients and methods:- A total number of 92 Egyptian postmenopausal women with and without osteoporosis were diagnosed by bone mineral density measurement were subjected to identification of VDR genes (FOKI and BSMI) polymorphism by PCR technique followed by RFLP analysis. Results:- The frequencies of BB, Bb and bb genotypes (BSMI polymorphism) in osteoporotic female were 58.7%, 32.6% and 8.7%, respectively. While, in controls their frequency was 8.7%, 17.4 % and 73.9%, respectively. The BB genotype was higher in patients than in controls (P = 0.000) while the bb genotype was significantly higher in controls than in patients. Regarding the FOKI polymorphism the frequencies of FF, Ff and ff genotypes among patients were 21.7%, 45.7% and 32.6%, respectively while their frequency in controls were 13%, 17.4% and 69.6%, respectively. We find out that the main predictors of osteoporosis are genotypes BB, Bb, ff in and number of pregnancy Conclusions:- Postmenopausal females carrying B+ve or f+ve genotype were more risky to develop osteoporosis. - See more at: http://www.journalijar.com/article/7255/association-between---vitamin---d-receptor-gene-polymorphisms-and-osteoporosis-in-post-menopausal-women-attending-zagazig-university-hospitals/#sthash.mJxjnd1t.dpuf
http://www.journalijar.com/article/7255/association-between---vitamin---d-receptor-gene-polymorphisms-and-osteoporosis-in-post-menopausal-women-attending-zagazig-university-hospitals/