: Background: The aims of this study are to (1) shed light on
the temporal relation between development of menopause and development of type
2 diabetes. (2) Clarify whether early menopause and short reproductive life
span could be considered as novel risk factor for type 2 diabetes. (3) Decide
whether type 2 diabetes is to be considered a cause and /or a sequel of early
menopause and short reproductive life span. Subjects and Methods: This study
was conducted on four hundred post menopausal women. Their ages? range was
(40-87y) with average mean (59.28?9.01y), a questionnaire was done to every
subject including reproductive factors, baseline characteristics, and
laboratory investigations. Results: our study was on postmenopausal women.
Their ages at menopause were (31-63) with mean average (47.73?5.02). The
prevalence of diabetes in post menopausal women was 38%. There was a
significant association between hyperglycemia and duration of menopausal status
after adjustment for age and other risk factors of diabetes with p < .001
& OR 1.04 . But no association was found between neither age at menopause
nor reproductive life span and the development of diabetes with p value 0.56,
0.92 respectively. There was a significant association between waist
circumference and risk of developing diabetes in post menopausal women with p
value .009 & OR .001. No significant association between hysterectomy and
risk of type 2 diabetes with p value 1. There was no significant association
between HRT & diabetes with p value .6. However, there was a significant
association between OCP and the risk of diabetes with p value .02 .There was a
significant association between gravidity and risk of diabetes with p .002 but
not with parity with p value .16. Conclusion: There was association between the
duration of menopause and development of type 2 diabetes. Waist circumference
representing central adipose tissue playing the major role in risk of diabetes
in postmenopausal women. - See more at:
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