CHANGES OF S. CARDIAC MARKERS AFTER ACUTE ATTACK OF MI BACKGROUND: Blood
testing for biomarkers of myocardial injury plays an important role for the
evaluation, diagnosis, and triage of patients with chest pain. The criteria for
the diagnosis of myocardial infarction have been redefined recently, as
reported in a document of the European Society of Cardiology (ESC) and the
American College of Cardiology (ACC), and require at least 2 of the 3 following
characteristics: (1) typical symptoms; (2) characteristic rise-and-fall pattern
of a cardiac markers or (3) a typical electrocardiogram (ECG) pattern involving
the development of Q waves. Currently serum troponins, can now detect extremely
small amounts of myonecrosis (<1.0 g), which, in the setting of an ACS, may
be associated with increased risk of complications. MATERIALS AND METHODS:
Patients are selected from those attending department of medicine, G.G.
Hospital, M.P. Shah Medical College, Jamnagar. Blood samples of patients were
taken to measure the serum LDH, Troponin I, CRP, CK-MB levels by ELISA (enzyme
linked immunosorbent assay) and their levels are compared with clinical
condition, ECG changes and prognosis of the patients. RESULT: Out of 100
patients studied 70 patients were in age group 40-70yrs, 74 patients were
having history of hyper tension and 55 patients were having complaint of chest
pain were diagnosed as having acute MI. CONCLUSION: Troponins are ideal markers
which enable early detection of patients with acute coronary syndrome whereas
inflammation markers are helpful in diagnosis and assessing the severity of
inflammation - See more at:
No comments:
Post a Comment