To know the etiology of septicaemia in
neonates. 2) To detect the antibiotic susceptibility of their isolates.
Materials and Methods: Blood specimens for culture were drawn from 729 newborns
admitted in NICU, Sri Venkateswara Ramnarayana Ruia Government General
Hospital, S.V.Medical College, Tirupati during March 2015 to August 2015 with
sepsis. The specimens were inoculated into Brain Heart Infusion broth &
subcultures were performed. The isolates were identified by standard
biochemical tests. Antibiotic susceptibility patterns of isolates were
identified by Kirby Bauer disc diffusion method. Results : A total of 53(7.27%
) organisms were isolated. These included Klebsiella (22, 41.54%), S.aureus
(17, 32.07%), Candida (8, 15.09%), E.coli (4, 7.54%), Pseudomonas (1, 1.88%),
Moraxella (1, 1.88%). Majority of organisms isolated were resistant to commonly
used antibiotics. Klebsiella showed maximum sensitivity to Levofloxacin
(85.7%). S.aureus showed maximum sensitivity to Levofloxacin (100%) &
Cefotaxime (88.8%). E.coli showed maximum sensitivity to Amikacin, Gentamycin,
Ciprofloxacin, Imipenem, Amoxyclav i.e., 100%. Conclusion: Multi drug
resistance organisms were isolated from septicaemia in neonates. Therefore
great caution is required in selection of antibiotic therapy. - See more at:
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