Background: Various studies showed statistically significant
association of high serum ferritin and AMI while some authors did not find any
significant association of high ferritin and AMI. The main objective of our
study was to compare the ferritin levels in cases and controls, in order to
assess the relationship of serum ferritin with AMI, in both univariate and
multivariate analysis, after controlling for established conventional risk
factors (like diabetes mellitus, hypertension, lipids, body mass index,
smoking, and alcohol intake). Materials and methods: The present study was
undertaken in the Department of General Medicine, S.V.S Medical College and
Hospital, Mahabubnagar during 1-8-2010 and 31-7-2014. A total of 150 patients
age, sex and Hemoglobin matched, were recruited from S.V.S Medical College and
hospital for the present study of which 75 subjects constituted the control
group called as the group A and remaining 75 subjects constituted the study
group called as group B. the above cases were recruited irrespective of
presence of any risk factors like hypertension, diabetes, smoking and alcohol.
Results and observations: The age of the patients varied form a minimum age of
30 yrs to a maximum of 70 years. The mean age of the patients in group A was
51.74 and the mean age in group b was 52.24, the mean age in two groups were
not significantly different from each other t = 0.265, p > 0.05. The mean
values for Total cholesterol, triglycerides, LDL, ferritin are significant
higher in group B compared to group A p < 0.001. The mean value of HDL is
significantly lower in group B compared to group A p < 0.001. Serum ferritin
was significantly higher in the study group and when compared with other
markers of myocardial injury this as significantly elevated as CPK, LDL and
SGOT. Conclusions: The univariate and multivariate analysis with serum lipids,
diabetes, hypertension, smoking and alcoholism and obesity showed and
independent risk factor and in the presence of other risk factors the risk
estimated to be much higher. - See more at:http://www.journalijar.com/uploads/460_IJAR-9016.pdf
No comments:
Post a Comment