Saturday, 14 May 2016

ANTIBACTERIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF WILD EDIBLE MUSHROOM PLEUROTUS OSTREATUSCOLLECTED FROM HIMACHAL PRADESH.

Objective:-The objective of present study was to identify the unknown wild edible mushroom based on morphological characteristics and DNA based sequencing by using universal primers ITS 1and ITS 4, antibacterial activity, phytochemical screening and FTIR analysis of mushroom extract spectra. Methods:- The wild edible mushroom specimen was tentatively identified morphologically and was cultured on 2% MEA. The isolate thus obtained was screened for its antimicrobial activity. Methanol extract was prepared in order to carry out antibacterial activity. The extract was subjected to qualitative phytochemicaland FTIR analysis. Results:-The isolates on the basis of morphological and molecular characterization was identified as P. ostreatus. Agar-well diffusion method was used to carry out antimicrobial assay. The methanolextract ofP. ostreatus showed antimicrobial activity against E.coli having zone inhibition diameter 24.3?0.5, against S. aureus having zone inhibition diameter 26.6?0.5,againstP. aeruginosa having zone inhibition diameter20.3?0.5 and against K.pneumoniae having zone inhibition diameter 28.6?0.5. Fourier transform infrared (FT-IR) analysis indicated that all mushroom?s extract spectra showed typical carbohydrate pattern with strong and broad absorption near 3300 cm-1which indicates the presence of OH group. Conclusion:-The isolate analysis have been showed to be good source of antimicrobial agent and phytoconstituents, therefore could be potential source of bioactive compounds with beneficial biological activities. - See more at: 

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