Background & Objectives: To investigate correlation between the ABO
blood groups and ovarian malignancies in females and also to correlate the
frequency of ovarian malignancies with Rh factor. Methods: Data were collected
on the blood groups of 1,870 females diagnosed with ovarian malignancies and
the same was compared with blood groups of 2,540 females taken as controls that
were operated with reasons other than ovarian malignancies. For assessing the
relationship between blood groups and ovarian malignancies, odds ratio (OR)
with 95% CI (confidence interval) was calculated. Results: A strong correlation
was observed between females without ‘A’ or ‘B’ antigens i.e. O blood group
females and increased risk of ovarian cancer (OR= 1.3281, CI= 1.1457-1.5396,
p-value= 0.0002). The strongest magnitude of correlation was observed in
patients without ‘Rh’ factor i.e. Rh- blood group. Interpretation &
Conclusions: There is a strong correlation between ABO and Rh blood groups and
tendency of a female to develop ovarian malignancy. - See more at: .
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