cardiovascular disease, but information on its
association with type 2 diabetes and mild nephropathy is limited. Diabetic
nephropathy (DN) is one of the most important microvascular complications of
diabetes. Aims and objectives:- The aim of the study was to find out the
relationship between plasma total homocysteine concentration, serum folate and
vitamin B12 in diabetic nephropathy in patients with type 2 diabetes mellitus.
Materials and Methods:- The study was conducted on total 90 subjects, out of
which 30 type 2 diabetics without nephropathy (group I), 30 type 2 diabetics
with nephropathy (group II) and 30 controls (age and sex matched) who were free
from any chronic disease. Plasma total homocysteine, folate and vitamin B12
levels were estimated along with routine biochemical parameters and compared
with healthy controls. Results:-Plasma total homocysteine levels were
significantly higher (p<0.001) in subjects with diabetic nephropathy than
without nephropathy and controls. - See more at:
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