The
present study was performed to evaluatethe safety and immunogenicity of
combined sheep pox (SP) and Peste des Petits ruminants (PPR) vaccine prepared
in a lyophilized form. A sheepgroup was vaccinated with the field dose of the
prepared combined vaccine subcutaneouslyand the cellular and humeral immune
responses of vaccinated sheep were evaluated for six months by different
serological tests and compared with the response of eachvaccine alone as a
control. It was found that the vaccinated sheep became protected from the 2nd
week post vaccination and keep the protective level till the end of the
experiment (24 week). The combined vaccine was found to be safe and potent as
evident from sero conversion as well as challenge studies in sheep. We
concluded that the use of the prepared combined vaccine component did not
interfere with each otherand can be used for economic vaccination strategies.see more
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