The present assays to diagnose kidney injurywithcreatinine/BUN
measurement can only detect this long time after the onset of kidney injury.
The aim of our study was to detect urinary low molecularweight (LMW) protein
for early diagnosis of renal disease. The dogs were clinically screened for
renal disease and separation of the urinary proteins by SDS-PAGE revealed low
molecular weight proteins at Mr~36.5 KDa, 21.9 KDa, and 14.4 KDa. Western
blotting revealed the presence of the retinol binding protein (RBP) among the
LMW proteins.RBP appears to be a specific, non-invasive bio-marker for
diagnosing dogs with renal failure. - See more at:
No comments:
Post a Comment