. This paper is focused on construction and investigating the
characteristics of novel levamisole (LVM) in situ modified polymeric membrane
sensors. Two sensors were prepared based on the cation exchangers
phosphotungstic acid and phosphomolybdic acid (PME1 and PME2, respectively)
using dibutyl phthalate as plasticizing solvent. These sensors showed Nernstian
slopes of 59.2±0.4 and 58.31±0.4 mV decade-1 in the concentration ranges
(1.0x10-6-1.0x10-2 and 1.0x10-5-1.0x10-2 mol L-1) with low detection limits
(1.0x10-6 and 2.8x10-6mol L-1) for PME1and PME2, respectively. The sensors were
found to be very selective and usable within a wide pH range (2-8). They
exhibited fast response times (? 10 s), good stability and long life span (40
and 37 days), respectively. LVM is determined successfully in pure solutions,
pharmaceutical preparations and biological fluids (human plasma, urine and
bovine milk) using the standard addition and potentiometric titration methods
with high accuracy and precision. - See more at:
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