. ionomer cement functionalized with ChlorhexidineHexametaphosphate
nanoparticles and Type II GIC. Methodology: Nine human premolars were used on
which Class I cavities measuring 5mm x 3mm x 2mm were prepared using round and
straight diamond abrasive. Specimens were divided into three groups. First
group of teeth specimens (n=3) were filled with GIC containing novel
antimicrobial nanoparticles composed of (CHX-HMP)
ChlorhexidineHexametaphosphate. Second group of teeth specimens (n=3) were
filled with Type II GIC .The third group of specimens (n=3) served as control
where no restorative material was filled. The samples were kept at 37 °C and
100% humidity for 3 days. Each tooth was sectioned into two half’s
mesio-distally using diamond disc. Teeth sections were evaluated for fluoride
uptake by dentin under SEM using EDAX image analyzer software. The results were
tabulated and analyzed. Result: The amount of fluoride present in Group I (Type
II GIC) was in the range of 7.64 atomic wt % and Group II (CHXHMP-GIC) was 6.71
atomic wt%.Flouride was detected till depths of 200 ?m for Type II restorative
GIC (Group I) and till 700?m for CHXHMP-GIC (Group II). Conclusion: Fluoride
release and consequent uptake by dentine was not significantly affected by the
substitution of antimicrobial nanoparticles. The fluoride penetration and its
effect on enhancing remineralization with the added antimicrobial effect of CHX
is promising. - See more at: .
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